Multidose vial contamination in anesthesia.
نویسندگان
چکیده
The intent of this research was to address the following question: Will an alteration in the drug aspiration technique cause a significant difference in the incidence of multidose vial contamination? The control group consisted of multidose vials collected at the end of each day from staff anesthetists. The use of these vials reflected the practice technique of a single needle and syringe for each vial. The vial, as well as needle and syringe, were used on all cases managed for the day. The experimental group consisted of multidose vials collected at the end of each day from the four investigators. The vials and syringes were utilized in the same manner as the control group with the exception that a new needle was used each time a vial was reentered. Upon completion of the collection period, guaiac testing, using Hemoccult slides and developer, was performed on a 0.1 cc sample from each vial. A multidose vial was considered positive for blood contamination if traces of blue appeared on the Hemoccult slide in a 15-minute period. A chi-square statistic was applied to the cumulative data. The control group consisted of 492 multidose vials. Of the 492 multidose vials tested, 11 were guaiac positive, 2.24%. The experimental group consisted of 369 multidose vials. Of the 369 multidose vials, one tested guaiac positive, 0.27%. A chi-square test on the cumulative data demonstrated a significant (p less than .05) difference between the two groups. The research demonstrated that occult blood may be contained within the used multidose vials suggesting that contaminated drug may then be injected into another patient.(ABSTRACT TRUNCATED AT 250 WORDS)
منابع مشابه
Multidose vials versus single-dose vials: a study in sterility and cost-effectiveness.
A total of 197 multidose injectable vials were collected from 10 different nursing stations and evaluated for sterility. Experimental contamination studies were undertaken, and the cost-effectiveness of multidose vials was compared with that of single-dose vials. Our results showed that bacterial contamination of multidose injectable vials was not a significant hazard; in addition, contrary to ...
متن کاملGlobal justice and the proposed ban on thimerosal-containing vaccines.
Thimerosal is an ethyl mercury–containing compound that has been used safely for .60 years as a preservative in multidose vials of vaccines to prevent bacterial and fungal contamination of those vials when they are repeatedly entered to withdraw doses. In the late 1990s, preservative-free single-dose vials were widely introduced into high-income countries (HICs). This was a precautionary move i...
متن کاملContamination of reconstituted multidose measles vaccine vial and toxic shock syndrome in Tamilnadu.
I read with interest and curiosity the Viewpoint and IAPCOI stand articles on AEFI with particular reference to measles vaccination related deaths in Tamil Nadu(1,2). I want to share my personal experience as a field investigator on similar measles vaccination deaths in Manali New town PHC (about 10 km from Chennai) way back in 1991-1992. At that time 6 children died. All of them developed high...
متن کاملSurvey of syringe and needle safety among student registered nurse anesthetists: are we making any progress?
Anesthesia providers serve a vital role in preventing the transmission of disease by following safe injection practices, yet violations of these standards have occurred. The goal of this study was to determine the extent of unsafe injection practices that exist among student anesthesia providers. An online survey containing 8 yes-no questions that assessed injection practices as outlined by the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- AANA journal
دوره 58 6 شماره
صفحات -
تاریخ انتشار 1990